I wouldn't totally write off Meetup.com. If you seriously feel you have NO real friends then at the very least its a way of forcing you to be social without necessarily having the whole pickup thing hanging over you... so that helps.
But yeah, I tried meetup and met some strange characters. Its not all bad but the premise for meetup is a lot of people who don't have friends to do stuff with and probably spend all day online, all go and "meetup" and its like a room full of sociallly awkward penguins. The upside being that since THEY are also nervous and not so talkative it gives you the chance to step up and take the lead, lead conversations, introduce people, social butterfly. At the very least it got me out from behind a computer and actually talking to more people.
Meetup can be a hit though if your town has any sort of groups who do regular bar crawls or drinks. I don't like advocating drinking too much if your not into it but the very nature of the group means they often draw big crowds and after a few drinks people get talking... so those sorts can be fun. Not everyone on meetup is antisocial, there's many like myself who are just new in town or their own friends don't enjoy the same activities.
Its always great to have a few "bros" though, for that I really recommend joining a sports team. There's lots of co-ed and social leagues around here. I love sports myseld but the ethos of these leagues is more about having a beer after than the actual score of the game... after a few games you'll have a bond going with the other guys as a team and see who's game for doing drinks the following weekend. This one was magic for me. But it doesn’t have to be a sport, it can be anything.
Friendships form over time not over-night. I am passionate about this topic because it was a big win for me this year. I learned a lot gaming solo and I still do it. But when you are solo, you are basically in your own head, then build yourself up to walk across the room for a big approach and then have to find a way to work it. While, with friends its as easy as turning to the girl next to me and opening with “Hey, how’s your night going?”
Another easy way to make othe guy friends is to use your skills with girls infront of them. DON’T boast, or show off. That’ll make them think you’re a dick. But if you can just chill with the guys and then turn to the girl next to you and get her group of friends engaging with you, then you seem like a good wingman. Guys like to go out with other guys who can bring girls to them.
And lastly… don’t make everything about game. If you went to a meetup, hit on every girl there, you soon have found yourself at a dead end. But if you go, make friends with a few, get invited to more outtings, then meet some of them and their seperate groups of friends outside of a meetup, then your circle grows exponentially. Its almost like a pyramid scheme

If you have 5 friends, who introduce you to 5 of their friends, who in turn introduce you to 5 of their friends… you see where this is going

Decide when and when not to game. Sometimes it’s better to just say that today I am going to this event to make friends who I can meet again, not hit on every girl until I run the place dry. At other times, decide to go picking up and go do it. Just decide.
And I’ll also add… don’t totally write off girls who are not 10’s as friends. Don’t write off guys who aren’t incredible PUAs themselves… judge people on their own merits and if they seem like people you can hang with, bring them into your circle, independant of PUA.