As I've mentioned once or twice, I almost pulled a woman in her 50s, she had a tight little well-exercised body and a very attractive attitude. I got cold feet though.
But yeah, no different really than any other pickup. I'd say vibe and energy is more important than game, if she's down she won't make it hard for you, probably her biggest fear is that you don't find her attractive.
During the approach (night street approach) we vibed so well that passers by were smiling. The insta-date was wine, great conversation and more vibing. We walked out arm in arm and she was giddily telling me she wasn't coming home with me (which meant that she was) but I let her down gently, got her number and bailed.
That said 60s/70s is well outside my wheelhouse. I usually don't even go for a woman in her 30s, but this was just something special in terms of instant connection.